A study of Correlation between HbA1c Level & Corneal Thickness in Diabetes Mellitus Patients

Abstract

Introduction: The purpose of this study is to find out the association of duration of diabetes and increased HbA1c level with corneal thickness in patients of DM. Materials and Methods: After obtaining approval by ‘Sumandeep Vidyapeeth Institutional Ethical Committee’, a comprised study of 150 type-II DM patients were conducted (only left eye included). All the patients underwent complete ophthalmic examination and all study procedure was performed after obtaining informed consent from all patients and in accordance with declaration of Helsinki. Result: The mean CCT of patients with DM <7 years was 543.1 (SD - 23.51) and that of patients with duration of DM ≥ 7 years was 546.95 (SD – 25.23). The difference was statistically insignificant (p value = 0.335). The mean CCT of patients with HbA1c <7% was 545.3 (SD – 24.31) and that of patients with HbA1c ≥ 7% was 545.1 (SD – 24.63). The difference was statistically insignificant (p value = 0.96) Conclusion: In our study we conclude that corneal thickness is not affected by DM, its duration and HbA1c levels.