Nanostructured Lipid Carriers: As an Efficient Drug Delivery Carrier

Abstract

oral route, it is used more predominantly for administration of variety of drugs. However, oral route is having certain issues regarding instability of certain drugs in upper gastro intestinal tract, poor solubility, first pass metabolism, fluctuation in blood plasma and inappropriate bioavailability with conventional dosage form. Therefore, there is a need for development of some novel carrier that can deliver the drug moiety efficiently with optimum therapeutic response. Since few years, Nanostructured lipid carriers are gaining attention of researchers towards suitable oral application of drug molecules. Nanostructured lipid carriers are superior then solid lipid nanoparticles with regards of drug entrapment and drug expulsion during storage period. This review shows some findings of Nanostructured lipid carriers of some drugs for improvement of their physicochemical properties