Diclofenac Induced Acute Kidney Injury: A Case Report

Abstract

Diclofenac is most commonly prescribed drug among Non Steroidal Anti Inflammatory Drugs (NSAID). Diclofenac is available in various form diclofenac sodium, diclofenac potassium, extended-release, enteric-coated, sustained-release, controlled-release, delayed-release, immediate-release, diclofenac topical, diclofenac epolamine, diclofenac gel, diclofenac powder etc. NSAIDs are having various Adverse Reactions (Table 1). A 65 years old male patient came to the tertiary care hospital in emergency condition. He was already known case of hypertension and medication history contained Tab. Amlodipine (15mg) (1-0-0). Medical history interview showed patient had toothache problem and has been taking OTC medication Tab. Diclofenac (1-1-1-1-1-1) (50mg) from 33 days. Laboratory reports showed a high level of Creatinine (1.7), which interpret that it is a case of Acute Kidney Injury due to Diclofenac.