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http://172.20.40.131:8080/jspui/handle/123456789/345| Title: | Aqua Mediated Sodium Acetate Catalysed One-Pot Synthesis of Pyrimidine Derivatives as Anti-Inflammatory and Antioxidant Agent |
| Authors: | Sureja, Dipen K. Dholakia, Sandip P. Vadalia, Kantilal R. |
| Keywords: | One Pot Synthesis Pyrimidine Derivatives Anti-Inflammatory Activity Antioxidant Activity |
| Issue Date: | 2016 |
| Publisher: | Der Pharma Chemica |
| Abstract: | The present investigation is focused on one pot synthesis of 6-amino-5-cyano-4-substituted-2-(hydroxy/mercapto) pyrimidine derivatives with the objective of discovering a novel and potent anti-inflammatory and antioxidant agent. The formation of compounds was recognized by preliminary laboratory techniques like melting point, Rf value and further confirmed by spectral analysis. Furthermore, they were screened in-vitro to study their anti-inflammatory and antioxidant activity, which shows moderate to good potency. |
| URI: | http://localhost:80/xmlui/handle/123456789/345 |
| ISSN: | 0975-413X |
| Appears in Collections: | Faculty Publications |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| aqua-mediated-sodium-acetate-catalysed-onepot-synthesis-of-pyrimidine-derivatives-as-antiinflammatory-and-antioxidant-ag.pdf | 131.08 kB | Adobe PDF |  View/Open |
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