Robinson Cytological Grading of Invasive Ductal Carcinoma of Breast And Comparison with Histological grading

Abstract

Background: Diagnosis of breast carcinoma is still made on fine-needle aspiration cytology (FNAC) in developing countries. Instead of merely reporting as benign or malignant, we should focus on extracting the maximum prognostic information from cytological smears so this will help clinicians to enhanced effects on the survival of patients using new chemotherapeutic agents. The Robinson et al introduce cytological grading system which is well corresponds to the histological grading method of Elston's modification of Scarff Bloon Richardson. Aims: This study was done to grade ductal carcinoma of breast and compares it with histological grading. Setting and design: Retrospective. Material and Methods: The present study was done over a sample size of 35 patients for over a span of 12 months. 35 Patients who went through FNAC and mastectomy for carcinoma of breast were cytological and histological graded. The results obtained by both grading methods were then compared. Statistical analysis: Comparison was done between these two grading systems and concordance rates were calculated between two grading system. Sensitivity and specificity were calculated for each cytological grade. Results: In the present study all were female. Oncology comparison of cytological and histological grades, 100% cases were grade III, 81% cases were grade II, 72% were grade I both on cytology and histology. Conclusion: The present study proves that, a simple cytological grading helps in evaluating the prognosis of the patient and provides varied treatment options depending on the grade.