Analytic Study of Gastrointestinal Tumours

Abstract

Background: GIST was introduced as a diagnostic term in 1983[1]. Until the late 1990s, many non-epithelial tumours of the gastrointestinal tract were called “gastrointestinal stromal tumours.” GISTs are a subset of mesenchymal tumours; represent the most common mesenchymal neoplasm of GI tract. [6] Aims and Objectives: To study the various location of the GIST at various parts of GI tract. Introduction: Gastrointestinal tumours are most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker intestinal cell of Cajal (ICC)[1]. GISTs occur in the stomach and small intestine with rare occurrence in the rectum (5%), colon (1%), oesophagus and appendix. e diagnosis of GIST is currently based on morphologic features and immune-histochemical demonstration of KIT (CD 117)[2]. Material and method: is study was performed in January 2015 to December 2016 at Dhiraj General Hospital Vadodara. Discussion: GISTs occurs in the entire gastrointestinal tract, A great majority of them occurs in the stomach (60 – 70 %), small intestine (25 –35 %), with rare occurrence in the colon(1%) and rectum (5%), oesophagus (<2%) and appendix. ey are rarely found in omentum and mesentery. GISTs are characterised by various symptoms abdominal pain, nausea, vomiting, GI bleeding and lump in abdomen [2]. Results: Male predominance was found in this study. Diagnosis was made based on clinical findings, ultrasonography, CT scan of abdomen, and based on intra-operative findings and postoperative histopathological and immunohistochemistry findings. It is estimated that incidence of GISTs is approximately 10 – 20 per million peoples, per year. Conclusion: is study shows male predominance, out of seven cases there were six male and one female patient. CT scan is ideal in defining endoluminal and exophytic extent of the tumours. e clinical presentation of GIST is variable but the most usual symptoms include the presence of mass or bleeding. Surgical resection of the local disease is the mainstay therapy.