Observational Study to Compare the Effect of Isobaric Ropivacaine 0.75% with Dexmedetomidine and Clonidine as an Adjuvant in Spinal Anaesthesia in Lower Limb and Lower Abdominal Surgeries

Abstract

Background and Objectives: Effect of intrathecal dexmedetomidine& clonidine as an adjuvant to isobaric ropivacaine in spinal anesthesia for lower limb & lower abdominal surgeries is not much studied. The objective was to assess the effect of dexmedetomidine 5 mcg & clonidine 30mcg as an adjunct to isobaric ropivacaine in spinal anesthesia. Materials and Methods: Sixty selected patients were randomized to receive intrathecal 0.75% isobaric ropivacaine 3ml with clonidine 30mcg & dexmedetomidine 5 mcg in spinal anesthesia for lower limb & lower abdominal surgeries. Block characteristics, hemodynamic changes, postoperative analgesia and adverse effects were compared. Results: Both groups were comparable regarding sensory & motor block characteristics and postoperative analgesia. Conclusion: We conclude that spinal anesthesia with isobaric ropivacaine 3ml with dexmedetomidine 5 mcg is better than clonidine 30mcg.