Multi-detector CT Evaluation of Liver Neoplasms

Abstract

Introduction: Introduction of Multi Detector computed Tomography has been a huge leap in the CT technology. MDCT has a high diagnostic accuracy, sensitivity and specificity in the evaluation of focal and diffuse lesions of liver. Current study aimed to study the role of MDCT as a diagnostic modality for the neoplastic lesions of liver, to diagnose and characterize focal liver lesions with help of Multidetector CT scan and to differentiate benign form malignant lesion and primary malignant from metastases. Material and methods: A prospective study of the role of MDCT in detecting and characterizing neoplastic hepatic lesions was conducted in the period from December, 2015 to December, 2017 in radiology department of Dhiraj Hospital, SBKSMIRC, Sumandeep Vidhyapeeth University, Pipariya, Vadodara. 80 patients, with hepatic neoplastic lesions, were selected. Diagnosis was confirmed by surgery and histopathology, follow up imaging and other non radiological investigations. Results: Out of 15 cases of Hepatocellular carcinoma 13 (86.67%) showed heterogeneous hyperenhancement in the arterial phase; 8 (53.33%) cases of hepatocellular carcinoma were hypoattenuating and 5 (33.33%) cases were isoattenuating in portal venous phase, suggestive of early washout. Out of 41 cases of metastases 39 (95.12%) cases of metastases showed hypoattenuation in arterial phase and portal venous phase while, in the venous phase 12 (29.27%) cases showed hypoattenuation and 27 (65.85%) cases showed isoattenuation. Out of 65 cases of adults with neoplastic lesions of liver including hepatocellular carcinoma, metastases, hemangioendothelioma, haemangioma and intrahepatic cholangiocarcinoma, sensitivity and specificity of MDCT for hepatocellular carcinoma was 86.7% and 98% respectively. Conclusion: MDCT is “The Imaging Modality of choice” in characterizing hepatic neoplasms and is highly sensitive for detection of hepatocellular carcinoma and hepatic metastases.