The Effect of Dentifrice Containing 1%Chloramine-T and Triclosan on Plaque and Gingival Status: An In-Vivo Comparative Study

Abstract

PURPOSE: Chloramine-T has been used in disinfecting impression material, dental appliances and in a dentifrice for total denture cleaning. Owing to the established causal role of bacterial plaque in gingivitis and the effectiveness of dentifrice in plaque control in addition to the toothbrush, it is appropriate to consider the role of Chloramine T in plaque control and compare it with commercially available triclosan containing dentifrice. Materials and Methods: A clinical, randomized, double-blind comparative study was conducted on 60 volunteers above 18 years belonging to the Sumandeep Vidyapeeth. Dentifrice containing 1% Chloramine T and a commercially available Triclosan containing dentifrice (Colgate Triple Action) were used in the study. The study subjects were divided into group Group I and Group II and were given dentifrice containing 1% Chloramine–T(experimental) and Triclosan (commercially available) respectively. Among the 60 volunteers the dentifrices were provided in identical, color coded tubes, and were instructed to use the dentifrices three times a day for the duration of 7 days. Results: Highly significant results were obtained after the intervention of commercially available Triclosan in case of plaque (p=0.000) and gingival status (p=0.001). Similar statistically significant results were obtained from Experimental dentifrice (1%Chloramine-T) for Plaque (p=0.001) and Gingivitis score (p=0.024). Conclusion: Chloramine-T and Triclosan had almost similar effect on gingival status and plaque. Chloramine-T can be used as an economical and affordable dentifrice at the community level.